*Note: This is a multiple select question, so more than one answer may need to b
ID: 140306 • Letter: #
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*Note: This is a multiple select question, so more than one answer may need to be selected in order to get the question correct.
Last answer choice is: mutations from one amino acid to another altering the characteristic of the amino aicd can effect a domain without effecting a motif.
9. Amino acids can be grouped into the following characteristic groups based on their R group: charged (basic and acidic), polar, and nonpolar. Given that information, which of the following statements accurately describes protein folding when mutations occur in a protein sequence? mutations from one amino acid to another within a characteristic group could have an effect on secondary structure without having an effect on tertiary structure mutations from one amino acid to another within a characteristic group will not alter primary structure mutations from one amino acid to another altering the characteristic of the amino acid may not effect secondary structure mutations from one amino acid to another altering the characteristic of the amino acid can effect a domain without effecting a motif Notes CommentsExplanation / Answer
Mutation from one amino acid to another in the same characteristic group could have an effect on the secondary structure without affecting the tertiary structure. e.g Lysine like arginine and histidine are basic polar amino acids in solution so are relatively equally positive. Replacing lysine with arginine would be conservative and attract the acidic polar charge of aspartic acid to be closest to keeping the same tertiary shape. {correct}
Primary structure of a protein is the sequence of amino acids in that protein so it will definitely be affected by the replacement of a protein. {not correct}
Secondary structure is formed primarily due to hydrogen bonds. So if the characteristic group is altered, the number of hydrogen atoms and hydrogen bonds will also be altered, hence changing the protein structure. {not correct}
A domain can exist independently and its structure is conserved. this is also the case for motifs. Motifs have a particular sequence of amino acids, therefore, it is unlikely that altering an amino acid can leave a motif unaffected. {not correct}
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