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1) Secondary structure of proteins. If one examines thestructures of proteins th

ID: 1399 • Letter: 1

Question

1) Secondary structure of proteins. If one examines thestructures of proteins that
cross membranes, the transmembrane regions are almost always alphahelices.

Why are alpha helices more common as transmembrane regions thanbeta sheets or
beta strands?
help on any of these would be apperciated

1) Secondary structure of proteins. If one examines thestructures of proteins that
cross membranes, the transmembrane regions are almost always alphahelices.

Why are alpha helices more common as transmembrane regions thanbeta sheets or
beta strands?
help on any of these would be apperciated

Explanation / Answer

Because    the   -helix is stabilized  by the hydrogen bonds  with the   same   peptide  chain along the helix .

While in  the      - sheet  structure   the  hydrogen bond is present within the same or different  peptides . In the   former  case   it is  by folding of the chain over itself  & in the later  the hydrogen bonds are formed  between   different   chains .