Which of the following statements describes NAD+? A. NAD+ is oxidized by the act

Question

Which of the following statements describes NAD+?
A. NAD+ is oxidized by the action of hydrogenates.
B. NAD+ is reduced to NADH during glycolysis, pyruvate oxidation, and the citric acid cycle.
C. NAD+ can donate electrons for use in oxidative phosphorylation.
D. In the absence of NAD+, glycolysis can still function.
E. NAD+ has more chemical energy than NADH.

Explanation / Answer

Best is option B. A. For reaction between two one-carbon compounds : CH3OH + NAD+ + dehydrogenase ----> CH2O + NADH + H+ + dehydrogenase (that is, the removal of two hydrogen atoms and their acceptance by NAD+) B. During glycolysis, 2 ATP molecules are used to phosphorylate and activate compounds that will eventually become converted to pyruvate and two hydrogen atoms are removed by NAD+ forming 2 NADH Pyruvate produced by glycolysis enters the mitochondrion and is converted to acetyl CoA . During this step, NADH is produced from NAD+ + 2H (oxidation) Most of the energy made available by the oxidative steps of the citric acidcycle is transferred as energy-rich electrons to NAD+, forming NADH. For each acetyl group that enters the citric acid cycle, three molecules of NADH are produced. D.In the absence of NAD+, glycolysis cannot function. As the primary purpose of glycolysis is the generation of ATP, NADH + H+, and pyruvate from glucose. E.NAD+ has less chemical energy than NADH.

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