79. Dose requirements for drugs with a narrow therapeutic range are most accurat

Question

79. Dose requirements for drugs with a narrow therapeutic range are most accurately calculated based on: a. age. b. body surface area (BSA). .sex. d. weight. 80. Based on the differences in metabolism of alcohol between the sexes, if both a man and woman consume the same amount of alcohol (on a weight-adjusted basis) and take the drug metronidazole, the disulfiram-like reaction between alcohol and the drug in the woman should: (Choose all that apply.) a. last longer than the man. b. c. d. abate sooner than the man. be more intense than the man. be less intense than the man. 81. Warfarin is a drug that is highly protein bound. If the nurse is administering warfarin to a malnourished patient with a low serum protein level, the nurse would expect the patient's response to the drug to be: a. more intense with a greater risk of bleeding. b. less intense with a greater risk for bleeding. c. more intense with a lesser risk for bleeding. d. less intense with a lesser risk for bleeding. Chapter 9,10 and 11 questions Your patient is breast feeding her child. Her physician orders a lipid-soluble drug for back pain. How will this be administered to help protect the baby? 82. Your patient, 7 weeks pregnant, comes in for her 1st prenatal visit. In the course of the assessment you ask what medications she is taking. She tells you she is taking a BP medication. What additional information do you need? 83. R4. Carol Smith, a 28-year-old woman with a history of severe epilepsy, is taking an antiepileptic drug. She has been seizure-free for a full year on this med. pregnant. her pregnanc ask the physician about this, and he might lead to this decision? She becomes Her neurologist and obstetrician consult and decide to continue the drug during y; you check your drug reference and see the drug is a class D. You politely acknowledges the risk but states it's necessary. What

Explanation / Answer

79. Drugs with narrow therapeutic range means that the drug have very low difference between therapeutic dose and toxic dose. Such drugs needs to given cautiously.

The answer is option (d) weight.

80. Disulfiram like reaction occur when alcohol is consumed with certain drugs interacting with alcohol. Women have lower efficacy to metabolize alcohol than men.

So the answer is (a) and (c)

81. The answer is (a). Low protein levels lead to over anticoagulation.

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