What is the expected result when two homologous chromosomes fail to separate dur
ID: 138189 • Letter: W
Question
What is the expected result when two homologous chromosomes fail to separate during meiosis I of spermatogenesis? A. Fertilization of this gamete may result in a zygote that is 48, XXYY. B. One gamete will have two of these chromosomes and one will have neither of these chromosomes. C. The risk for development of polygenic disorders is increased with fertilization of the polar body associated with this mature gamete. D. Increased genetic diversity is possible with fertilization of any of these four gametes because of an increased number of possible gene alleles.
Explanation / Answer
Answer: The risk for development of polygenic disorders is increased with fertilization of the polar body associated with this mature gamete.
It causes a mutation in the number of chromosomes, either extra chromosomes or missing chromosomes. Nondisjunction during meiosis can cause chromosomal disorders, such as trisomy 21 (Down syndrome), Turner's syndrome, and Klinefelter's syndrome.
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