. (10 points) According to the nursing notes, at least 36 minutes passed before

Question

. (10 points) According to the nursing notes, at least 36 minutes passed before the hospital staff realized something was wrong. Azithromycin is usually administered intravenously over a concentration range of 1.0-2.0 mg/mL over a period of one hour. Consider a hypothetical situation whereby a dose of 500 mg of azithromycin is administered at 2.0 mg/mL of azithromycin in 'a normal saline a) How many mg of medication would have been administered every 15 minutes? (b) Plot a graph of dose administered vs, time c) Using the graph only, determine how much medication would be administered in 36 minutes (d) What % of medication (relative to the total dose of 500 mg) would be administered by 36 minutes? md au m

Explanation / Answer

a.(ans) .

Usual administration of azithromycin is 1.0 to 2.0 mg/ml over an hour , and prescribed dose is 500 mg . In given situation 500 mg of azithromycin is diluted in 250 ml solution ,

In 60 min -----------------------500mg

So in 1 min----------------------500/60

In 15 min--------------------------500/60×15. = 125 mg

b.(ans).  

  

c.(ans)....... 300mg administered in 36 minutes.

d.(ans). percentage of drug administered in 36 minutes

300/500 ×100%=60%

e.(ans). 2mg...........1 ml of azithromycin

1 mg ...........1/2ml

300mg...........1/2×300 = 150 ml in 36 minutes.

  

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