50. The negative regulator of the lac operon is encoded by the positive regulato

Question

50. The negative regulator of the lac operon is encoded by the positive regulator of the lac operon is the gene and the complex 51. The active repressor is formed by the combination of molecule known as the co-repressor. and a small 52. The lacl gene is a regulatory gene in which the product is that keeps the system turned off. proteins 3.Some genes exhibitwhich means that the protein product of a gene regulates its own transcription 54. The type of gene expression, which is constant and independent of on off regulatory control, is called 55. The continue through the ttp operon or be terminated prematurely gene expression. mechanism controls whether transcription, once started, will synthesis of ß-Galactosidase only 56. A lacO mutation causes when the lacO and lacZ alleles are contained in the same DNA molecule either overlap or be 57. Regulation of the lac operon requires that the adjacent to the promoter of the structural genes because binding with the repressor prevents motif that is called 58. Many transcriptional activator proteins include a a zinc finger because the folded structure incorporates a zinc ion. 59. Some genes are also subjected to regulation by transcriptional which are short nucleotide sequences that are targets for DNA-binding proteins that, once recruited to the site, the assembly of large protein complexes that prevent transcription 60. The development of the mammalian immune system involves 61. A regulatory base sequence in eukaryotic cells that increases the rates of transcription of nearby genes regardless of orientation is called a(n) . refers to heritable changes in gene expression that are not due 62. to changes the DNA sequence itself, but to something "in addition to" the DNA sequence, usually either chemical modification of the bases, or protein factors bound with the DNA 63. Several different multiprotcin complexes, known as identified that can restructure chromatin and enable it to be transcribed have been 64. The primary transcripts of many gencs in cukaryotes are different to yield

Explanation / Answer

50. The negative regulator of lac operon is encoded by lacI

while the positive regulator is complex of cAMP-CAP.

51. Allorepressor and co repressor combinely form active repressor.

52. lacI gene forms repressor protein which keep transcription turned off.

53. Allsoterism of gene lead to the property that protein product regulates its own gene regulation.

54. Constitutive gene expression is constant and independent of on and off regulatory element. It once start keeps on going.

55. Atteneuation mechansim is for constitutive expression which means the protein expression once started will continue through trp operon

56. LacOc will cause constitutive synthesis of beta galactosidase.

57. Operator should overlap or adjacent to the promoter to prevent repressor binding.

58. DNA binding motiff is present in transcriptional actiovator protein containing zing finger.

59. Silencers: Some genes are also subjected to regulation by transcriptional silence which are short nucleotide sequences that are targets for DNA-binding proteins that, once recruited to the site, promote the assembly of large protein complexes that prevent transcription.

60. Programmed deletions are involved in development of immune system in mammals.

61. A regulatory base sequence in eukaryotic cells that increases the rate of transcription of nearby genes regardless of orientation is called an enhancer.

62. Mutation is the heritable change that occurs in DNA sequence and alters its expression.

63. Chromatin remodelling complex are involved in restructuring of chromatrin.

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