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he phospholipid molecule PIP2 (phosphatidylinositol 4,5-bisphosphate) is an impo

ID: 1349666 • Letter: H

Question

he phospholipid molecule PIP2 (phosphatidylinositol 4,5-bisphosphate) is an important constituent of eukaryotic cell membranes. Its hydrophilic head group has a greater negative charge (typically -4e under physiological pH) than most of the other phospholipids present in eukaryotic cell membranes. PIP2 makes up only a small fraction of the membrane (typically ~1% by mole fraction), but in spite of this low concentration, it is known to form clusters with multiple PIP2 molecules that are thought to be important in cell signaling. It is an area of active research to understand the basis of this cluster formation.

A simplified model of such a cluster consists of five PIP2 molecules, each with a headgroup charge of –4e, and four Ca2+ ions. They are all placed on a grid where each grid square has sides of length s, as shown in the figure at the right.

How many electric forces are there on the ion in the middle, labeled "2"?

Answer:

What is the direction of the total electric force on this ion? Enter "u" (up), "d" (down), "l" (left), "r" (right), "0" (zero force), or "N" (none of these).

Answer:

Explanation / Answer

0 (zero force)

Since the other charges are distributed symetrically, Net force on center charge will be zero.

It means equal and opposite forces act in -x and +x direction.

equal and oppsite forces act in -y and +y direction.