Natasha was certain she was looking younger despite her 58 years on this Earth.

Question

Natasha was certain she was looking younger despite her 58 years on this Earth. Every day in the mirror her lines seemed to disappear. She had searched so long for something to slow the process of aging; her marriage depended on it! Vladimir would never stay with her if he saw the wrinkles she did! Even her precious parrot, Bruno, had noticed and shied away from her! She could never live without him so she tried it all: mercury creams, Botox, weight pills from the ancient woman in the south side market of Moscow, Switzerland’s best cell therapy, and one pint of honey and another of yogurt every day! But a week or two after her “youth” came back she wasn’t feeling nearly so good…. Finally she went to the hospital because her fever was so high (102.8). She also had a non-stop horrible cough, muscle aches, vomiting, diarrhea, and a terrible headache. As the attendant physician at the hospital you try to narrow it down based on the patient profile, potential exposures and symptoms. ?
1) What are the top five infectious diseases? Justify your choices. 2) You send off for some laboratory tests right away and find the information below. Explain these results. Does this change your diagnosis? If so how? (6 points) a. Leukocytes – 6,000,000,000/L b. Platelets – 700,000/ L c. RBC – 450,000,000/L d. Hb – 14g/dL e. HCT% - 49 f. Bilirubin – 6 mg/dL g. Creatinine – 0.97 mg/dL
3) Natasha’s cough got worse and worse and the clock seemed to be ticking. The results of the molecular and immunological panel are below. Has your reasoning been confirmed? Interpret them and describe how they work. (12 points)
a. Western immunoblotting (first lane ladder, second Natasha’s blood, third positive control, fourth negative control)

Natasha was certain she was looking younger despite her 58 years on this Earth. Every day in the mirror her lines seemed to disappear. She had searched so long for something to slow the process of aging; her marriage depended on it! Vladimir would never stay with her if he saw the wrinkles she did! Even her precious parrot, Bruno, had noticed and shied away from her! She could never live without him so she tried it all: mercury creams, Botox, weight pills from the ancient woman in the south side market of Moscow, Switzerland’s best cell therapy, and one pint of honey and another of yogurt every day! But a week or two after her “youth” came back she wasn’t feeling nearly so good…. Finally she went to the hospital because her fever was so high (102.8). She also had a non-stop horrible cough, muscle aches, vomiting, diarrhea, and a terrible headache. As the attendant physician at the hospital you try to narrow it down based on the patient profile, potential exposures and symptoms. ?
1) What are the top five infectious diseases? Justify your choices. 2) You send off for some laboratory tests right away and find the information below. Explain these results. Does this change your diagnosis? If so how? (6 points) a. Leukocytes – 6,000,000,000/L b. Platelets – 700,000/ L c. RBC – 450,000,000/L d. Hb – 14g/dL e. HCT% - 49 f. Bilirubin – 6 mg/dL g. Creatinine – 0.97 mg/dL
3) Natasha’s cough got worse and worse and the clock seemed to be ticking. The results of the molecular and immunological panel are below. Has your reasoning been confirmed? Interpret them and describe how they work. (12 points)
a. Western immunoblotting (first lane ladder, second Natasha’s blood, third positive control, fourth negative control)

Natasha was certain she was looking younger despite her 58 years on this Earth. Every day in the mirror her lines seemed to disappear. She had searched so long for something to slow the process of aging; her marriage depended on it! Vladimir would never stay with her if he saw the wrinkles she did! Even her precious parrot, Bruno, had noticed and shied away from her! She could never live without him so she tried it all: mercury creams, Botox, weight pills from the ancient woman in the south side market of Moscow, Switzerland’s best cell therapy, and one pint of honey and another of yogurt every day! But a week or two after her “youth” came back she wasn’t feeling nearly so good…. Finally she went to the hospital because her fever was so high (102.8). She also had a non-stop horrible cough, muscle aches, vomiting, diarrhea, and a terrible headache. As the attendant physician at the hospital you try to narrow it down based on the patient profile, potential exposures and symptoms. ?
1) What are the top five infectious diseases? Justify your choices. 2) You send off for some laboratory tests right away and find the information below. Explain these results. Does this change your diagnosis? If so how? (6 points) a. Leukocytes – 6,000,000,000/L b. Platelets – 700,000/ L c. RBC – 450,000,000/L d. Hb – 14g/dL e. HCT% - 49 f. Bilirubin – 6 mg/dL g. Creatinine – 0.97 mg/dL
3) Natasha’s cough got worse and worse and the clock seemed to be ticking. The results of the molecular and immunological panel are below. Has your reasoning been confirmed? Interpret them and describe how they work. (12 points)
a. Western immunoblotting (first lane ladder, second Natasha’s blood, third positive control, fourth negative control)

Explanation / Answer

1) The top infectious diseases include,

Decreased immunity due to diet restriction may have lead to the development of infectious disease in this patient.

2) The laboratory results show that there is leucocytosis, increased platelet count and bilirubin. Leucocytosis indicates disease such as tuberculosis or pertussis. Increased bilirubin may have caused due to hepatic pathology.

3) Persistent cough point towards respiratory infections like tuberculosis.

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