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2. A: A large quantity of K ions are added to the extracellular fluid of a neuro

ID: 134271 • Letter: 2

Question

2. A: A large quantity of K ions are added to the extracellular fluid of a neuron. The neuron is then stimulated to generate an action potential. During this action potential, how will the addition of K' to the extracellular fluid influence the repolarization and hyperpolarization phases of the action potential? Explairn. B: Following this action potential, how will the neuron's resting membrane potential compare to its resting membrane potential prior to thea ddition of K'? C: How will the addition of Kt to the extracellular fluid affect the neuron's overall function? Why? (Hint: Injections of potassium chloride solution are lethal).

Explanation / Answer

1. In this case depolarisation will occur because presence of positice ions in extracellular matrix will make membrane potential less negative.

2. IN this case the resting poteintial will become more postive or less negative. In normal conditions the resting potential is -60 to -70 millivolts. But presence of k+ ions will make the membrane potential more postive.

3. The increase in the concentration of k+ ions outside will adversly affect the neuron health because the resting potential has to be kept constant for smooth functiong of ion channels.

In normal process when depolarisarion occurs Na+ channels open and action potential increases upto +40mV then K+ ion channels open and potassium ions are exported to maintain the resting poteintial.