The Sic Homology 2 (SH2) domain is highly specific for phosphorylated yrosine re

Question

The Sic Homology 2 (SH2) domain is highly specific for phosphorylated yrosine residues and is expressed across nearly all species. Which of these proteins is most likely to contain an SH2 domain? a PI3K, a cellular signaling enzyme activated when IGF-1 binds its receptor tyrosine kinase b Adenylyl cyclase, an enzyme activated by Gs following stimulation of beta-adrenergic receptors Oc CaMKII, a kinase stimulated by elevated intracellular calcium o a. d Phospholpase C (PLC), an enzyme that cleaves phosphate groups from a number of various phospholpids

Explanation / Answer

I believe the correct answer to be A) PI3K due to the fact that it is involved in RTK pathway where the signal is atleast initially transfered from one molecule to another by phosphorylation of Tyrosine.

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