16. The following statement is true about a tunor suppressor gene mutation to in
ID: 133969 • Letter: 1
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16. The following statement is true about a tunor suppressor gene mutation to induce cell division of a mammalian cell: A) proto-oncogene product must have decreased activity. B) tumor suppressor gene product must lose activity C) tumor suppressor gene product must have an increased activity D) profo-oncogene must lose ability to express mRNA. 17. Incidence of cancer in human increases with age suggesting that: A) cancer is an infectious disease. B) multiple mutations are required to develop cancer C) cancer gene(s) cannot acquired in lifetime. D) none of the above are 18. Plasmids are important in biotechnology because they are: A) a vehicle for the insertion of foreign genes into bacteria. B) recognition sites on recombinant DNA strands. C) surfaces for protein synthesis in eukaryotic recombinants D) surfaces for respiratory processes in bacteria. E) proviruses incorporated into the host DNA. 19. What is the enzymatic function of restriction enzymes? A) to add new nucleotides to the B) to join nucleotides during replication C) to join nucleotides during transcription D) to cleave nucleic acids at specific sites E) to repair breaks in sugar-phosphate backbones 20. What is a cloning vector? A) an enzyme that cuts DNA into restriction fragments B) a DNA probe used to locate a particular gene in the genome C) an agent, such as a plasmid, used to transfer DNA from an in vitre solusion into living cell D) the laboratory apparatus used to clone genes E) the sticky end of a DNA fragment 21. Bacteria containing recombinant plasmids are often identified by which process? A) examining the cells with an electron microscopo B) using radioactive tracers to locate the plasmids C) exposing the bacteria to an antibiotic that kills cells lacking the plesmid D) removing the DNA of all cells in a culture to see which cells have plasnids E) producing antibodies specific for each bacterium containing a recombinant plasmid 22. How does a genomie library differ from a cDNA ibrary? A) A genomic library contains both soncoding sequences and coding sequemces, whercasExplanation / Answer
16. Tumour suppressor gene are genes product of which are involved in cell divison. Option B is correct.
17. None of these are true. Chance of cancer increases due to accumulation of toxic wastes. Option D.
18. Plasmids are extrachromosomal DNA for transfer of foreign DNA into bacteria. Option A is correct.
19. Restriction enzymes are also called molecular scissors and make cut on specific sites. Option D is correct.
20. Cloningg vectors are agents to clone DNA or gene into living cells. Option C is correct.
21. Generally recombinants are selected by applying antibiotic. Recombinamts are survived in antibiotic solution due to product of marker gene. Option C is correct.
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