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1. Match the options below to Correct Answer Choice: Cell death due to injury is

ID: 133053 • Letter: 1

Question

1. Match the options below to Correct Answer Choice:

Cell death due to injury is called:

a. apotosis b. necrosis c.infarction d. ischemia

Necrotic cell death due to ischemia is called:

a. necrosis b. infarction c. reperfusion injury

The reversible response of cells to stressful stimulus is called:

a. apoptosis b. cell injury c. adaptation d. hydropic change

The compartment formed when an autophagosome uses with a lysosome is called:

a. amphisome b. vacuole c. apoptosome d. none of the above

Low oxygen levels caused by reduced blood supply is called:

a. hypoxia b ischemia c. reperfusion injury d. oxidative stress

Another term for a blood clot is:

a. atheroma b. thrombus c. fatty streak d. none of the above

2. Need to fill in the gaps .....

In response to stress, cells have evolved elaborate signaling pathways that enable the sensing of imbalances of crucial variables. Complete each statement below by typing the correct answer in each answer box. Please use all capital letters.

1)............................. is a stress response to low oxygen levels and involves the oxygen sensor, HIF1 alpha.

2) ................acts as an indirect sensor of DNA damage caused by double stranded breaks and can trigger cell cycle arrest or apoptosis.

3) When unfolded proteins accumulate in the cytosol, a transcription factor is freed to enter the nucleus and drive the expression of.................... , which inhibits apoptosis. This response pathway is called the...................... response.

4) When amino acid levels are low, the enzyme,.................................... binds uncharged ............................molecules and responds by inhibiting global translation.

5) An accumulation of unfolded proteins in the ER is sensed directly by the protein,............................. , rendering it unable to inhibit 3 key membrane proteins: PERK, ATF4, and.................................... .

Explanation / Answer

Option B is correct. Cell death due to injury is called necrosis.

Option B is correct. Necrotic cell death due to ischemia is called infarction.

Option C is correct. The reversible response of cells to stressful stimulus is called adaptation.

Option A is correct. Low oxygen levels caused by reduced blood supply is called hypoxia.