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One of the hallmarks of DNA polymerase is its quality of exclusively reading DNA

ID: 132806 • Letter: O

Question

One of the hallmarks of DNA polymerase is its quality of exclusively reading DNA from 3' 5' and synthesizing DNA from 5'-3'. Imagine an organism whose DNA polymerase mutates and gains the ability to read DNA in both directions. How would the mutated polymerase differ from the original enzyme? Oa Due to changes in its proofreading ability, the mutated enzyme would produce strands with overlapping sequences. Ob. The telomeres of the strand made by the mutated polymerase would be unusually short. OC. Replication mediated by the mutated polymerase would require increased ligase activity Od. Okazaki fragments would not be observed in replication governed by the mutant polymerase.

Explanation / Answer

C - Replication mediated by the mutated polymerase would require increased ligase activity.

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