Design an epidemiological study for the scenario below and provide at minimum th

Question

Design an epidemiological study for the scenario below and provide at minimum the following information about your study. If one of the questions isn’t applicable to your study, respond N/A after the question.:

Scenario: A researcher wants to study whether women who breastfeed have lower rates of breast cancer in later life. Funders would like an analysis within two to three years.

Study type (observational or experimental)

Study design (randomized trial, cohort, case-control, or cross-sectional)

Study hypothesis

Define your target population

Describe how you will recruit or identify study participants to best represent the target population

Describe the risks and benefits of participating in the study

Provide a case definition (e.g. in a cohort study, how will you diagnose those who become ill, in a case-control or cross-sectional study, what characteristics does the participant need to have to be considered a case)

Describe exposures or risk factors and how you will measure them

Describe exclusion criteria (e.g. in a prospective cohort study, a person who tests positive for illness at or near baseline must be excluded)

Describe how you will collect data for your study (survey, medical records, laboratory tests, etc.)

Divide subjects as appropriate for your study design (i.e. exposed/unexposed, case/control)

Describe outcome measure for study, how it’s calculated, and how it’s to be interpreted (you don’t need to actually do calculations, but provide the equations and give an example of how they’re interpreted): For example: RR=a/(a+b) interpreted as the risk of lung cancer in smokers is X times greater (or less) than it is in non-smokers

Give justification for your study design (tell why you chose that particular study design, why it is appropriate, and what you hoped to learn from doing the study)

Brief discussion of study strengths and weaknesses including a discussion of causal hypotheses and biases as they relate to your study design

Explanation / Answer

1. The study should be an observation study. It can also be an experimental study but since cohort design will be most helpful for the study, an observation study will be preferred.

2. Study design will be cohort design which are usually prospective in nature and helpful in finding links between disease condition and it's risk factors.

3. Hypothesis

H0 - there is no difference in the rate of occurance of breast cancer in later life due to breast feeding in earlier life.

H1- there is a difference in the rate of occurance of breast cancer in later life due to breast feeding in earlier Life

4. Target population with be consisting of all mother's who adopt breast feeding for their child.

5. Identification and recruitment of samples can be done by visiting lactation centres, antenatal clinical, post natal clinics as well as community where mother's have adopted breastfeeding for their young ones

6. Risk of participating in the study - there's no risk in this study as it is an observational study and each mother's descision is being respected.

Benefits of the study can be short term and long term.shirt term will include optimum nutrition to child, better immunity for child, mother can regain her original weight, strong bond between mother and child. Long term effects will include prevention of disease such as breast cancer.

7. Case definition can also be considered as inclusion criteria.

A. Mother's who have delivered their children

B. Mother's who have opted for exclusive breastfeeding for six month.

C. Mother of age between 18-35.

8. Risk factors

9. Exclusion criteria - mother's who are contraindicates for breast feeding due to medication or treatment to the mother or disease condition.

Infants who are suffering with galactosemia.

10. Data collection will be done observation, interview and physiological measurements. Physiological measurements will include laboratory studies and health records which will be studied upon.

11. Cohort group is mother's who have adopted breastfeeding. Division of subjects are : breastfeeding mothers/ non breastfeeding mothers.

12. Calculation of outcome of study - paired t tes or wilcoxin testing can be utilised to the to analyse the statistical outcome.

13.study design to be uuaed for this stiy is cohort design. This design givea a prospective outlook which can be measured periodically and the outcome can be assessed. This design is mainly used in medical and nursing studies which can give cause effect relationship between risk factor and the. Disease condition. This study will help me analysis and researching about the relationship between breastfeeding and prevention of breast cancer.

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