Your 59-year old male pateint is in the clinic today reporting that he thinks so

Question

Your 59-year old male pateint is in the clinic today reporting that he thinks something is wrong with his week old ileostomy. He also reports burning during urination. Before the nurse practioner sees the pateint, you reveiw his medications. He does not have a list of medications, so you review his chart and then review his medications with him.

Home Medications:

Atropine .3 my every 4-6 hours as needed

Chlordiazpoxide(Librium) 5 mg every 8 hours

Cholestyramine (Questran) 4 mg every morning

Desvenlafaxine (Pristiq) 50 mg 1 tab every morning

Ibuprofen (Motrin) 800 mg as needed for pain

Potassium Chloride 10 mEq 1 tab every morning

Sildenafil (Viagara) 25 mg 1 hour prior before sexual activity

Does the indivuals medical history have an effect on the pharmokinetics of each drug??

*Please answer the question pertaining to this persons specific medical history and the way his history would effect how each drug works. Thank you.

Explanation / Answer

Pharmacokinetics of ileostomy patients is rare because each stoma is unique and generalizations are difficult to make; however, in the treatment of ileostomy patients, drug malabsorption is a major obstacle. Crushing/ pestling, solving/make a suspension can reduce the malabsorption problem.

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