she can still take it for her headaches. What will you tell her? fu- 16. Randy h

Question

she can still take it for her headaches. What will you tell her? fu- 16. Randy has a history of hypertension and coronary artery disease. Today he is being evaluated for acute gout, and the prescriber is considering febuxostat (Uloric). Are there any concerns, based on Randy's history, if he takes this drug for gout? Explain your answer us- ck ory CASE STUDY Read the scenario, and answer the following questions on a separate sheet of paper. he Sadie has been taking indomethacin (Indocin) as part of therapy for osteoarthritis but lately has noticed that it has been less effective. Her provider has decided to try celecoxib (Celebrex). Sadie has a history of hepatitis (15 years earlier) 1. What advantages might there be to treatment with celecoxib rather than indomethacin? 2. What potential adverse effects will you warn Sadie u about before she takes this medication? What should she report 3. What allergies are important to assess before Sadie takes this medication? 4. She asks you if she can drink her usual glass of wine each evening while taking this medication. What will you tell her?

Explanation / Answer

Ans 1: The celecoxib has fewer side effects on the stomach as compared to indomethacin. Moreover, taking indomethacin for longer duration can cause serious side effects. Adding further since Sadie has osteoarthritis which is an inflammatory condition, she will definitely get more benefits with celecoxib because it acts as anti-inflammatory also.

Ans 2: Potential side effects associated with celecoxib are

Indigestion, nausea, vomiting, headache, bloating, abdominal discomfort

Severe stomach or intestinal ulcers

chest pain, weakness, breathlessness, altered speech, vision abnormalities with balancing disturbances.

Dark to tarry coloured stool. It can also associate with blood in stools.

Blood stained vomitus

rapid weight gain

Renal toxicity and hyperkalemia

Heart failure

Haematological toxicity

She should report any symptoms associated with the above mention side effects.

Ans: 3: Any allergy to celecoxib

Any allergy to NSAID or aspirin

Any kidney or liver disease should be reported upfront

Ans 4: It can interact with wine and can cause serious interaction complications, hence, it should be avoided with wine.

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