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Of 2, 872 persons who had received radiation treatment in childhood because of a

ID: 121848 • Letter: O

Question

Of 2, 872 persons who had received radiation treatment in childhood because of an enlarged thymus, cancer of the thyroid developed in 24 and a benign thyroid tumor developed in 52. A comparison group consisted of 5, 055 children who had received no such treatment (brothers and sisters of the children who had received radiation treatment). During the follow-up period, none of the comparison group developed thyroid cancer, but benign thyroid tumors developed in 6. Calculate the relative risk for developed in benign thyroid tumors: 15.3 Questions 2 and 3 are based on the information given in the following table.

Explanation / Answer

AR = Absolute risk= Number of events in treated or control / Number of people in that group

ARC = AR of events in the control group

= relative risk for benign thyroid tumors in control group

= 6/5055

ART = AR of events in the treatment group

= relative risk for benign thyroid tumors in treatment group

= 52/2872

Relative risk for benign thyroid tumors = ART / ARC

= ( 52/2872) / (6/5055)

= 15.25

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