The alpha-1 blockers can cause reflex tachycardia as a side effect. Carvedilol i
ID: 11238 • Letter: T
Question
The alpha-1 blockers can cause reflex tachycardia as a side effect. Carvedilol is an alpha-1, beta-1, beta-2 blocker. However, carvedilol does NOT cause reflex tachycardia even though it is an alpha-1 blocker. Which statement best explains why?A. Baroreceptor will kick in but it will be blocked because the drug also directly lowers heart rate (beta-1).
B .Carvedilol is only a very weak alpha-1 blocker so the baroreceptor doesn't kick in.
C. Blocking beta-2 receptors causes reflex bradycardia that counteracts the reflex tachycardia.
D. Carvedilol is only used to treat heart failure and it is impossible for a patient with heart failure to get tachycardia.
Explanation / Answer
The alpha-1 blockers can cause reflex tachycardia as a side effect. Carvedilol is an alpha-1, beta-1, beta-2 blocker. However, carvedilol does NOT cause reflex tachycardia even though it is an alpha-1 blocker. Which statement best explains why?
A. Baroreceptor will kick in but it will be blocked because the drug also directly lowers heart rate (beta-1).
B .Carvedilol is only a very weak alpha-1 blocker so the baroreceptor doesn't kick in.
C. Blocking beta-2 receptors causes reflex bradycardia that counteracts the reflex tachycardia.
D. Carvedilol is only used to treat heart failure and it is impossible for a patient with heart failure to get tachycardia.
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