3. Glycolysis and the TCA cycle are regulated by small molecules and the energy

Question

3. Glycolysis and the TCA cycle are regulated by small molecules and the energy state of the cell. (4 points) a) Give one example of an enzyme from each pathway that is regulated by ATP and identify whether the enzyme is inhibited or activated (circle one). Glycolysis enzyme:_ TCA cycle enzyme b) Why is ATP a shared regulator of both of these pathways? INHIBITED or ACTIVATED INHIBITED or ACTIVATED c) Several TCA cycle intermediates regulate glycolytic enzymes. Name a glycolytic enzyme and the TCA intermediate that regulates its activity. Why would this type of regulation benefit the cell?

Explanation / Answer

a, Glycolysis enzyme is inhibited and TCA cycle enzyme is Activated.

b.Because the two pathways complement each other.In that the energyreleased from one is used up by the other.

c.glucose 6 phosphate and hexokinase respectively

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