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4th option: The I2 serves as a Lewis Acid to activate the Ag2SO4, then the aroma

ID: 1035853 • Letter: 4

Question

4th option: The I2 serves as a Lewis Acid to activate the Ag2SO4, then the aromatic ring attacks the activated sulfate electrophile to substitute ortho to the NH2 group.

12, Ag2S04 NH2 Based on you knowledge of EAS, which answer best describes this reaction, which is used by my research students as the first step n the synthesis of an amino acid. o The silver (Ag) compound serves as a Lewis acid to activate the l then the aromatic ring attacks the activated halogen electrophile to substitute ortho to the NH2 group The 1l2 serves as a Lewis acid to activate the Ag2So4, then the aromatic ring attacks the activated sulfate electrophile to substitute ortho to the CN group. The silver (Ag) serves as a Lewis acid to activate the I2, then the aromatic ring attacks the activated halogen electrophile to substitute ortho to the CN group.

Explanation / Answer

The silver compound act ase lewis acid to activate I2, Then the aromatic ring attacks the actvated halogen to substitute ortho position to the NH2 group

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