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1.) If you can taste the chemical PTC, it means you have at least one copy of a

ID: 10344 • Letter: 1

Question

1.) If you can taste the chemical PTC, it means you have at least one copy of a dominant gene C. If you can't taste it, you have two copies of the recessive allele for tasting PTC - allele cc. A man who can taste PTC marries a woman who can also taste PTC. Both partners each have one parrent who cannot taste PTC and one who can. If this happy couple plans to have eight children, about how many of their children do you predict will be able to taste PTC?ing PTC- allele cc.

2.) Let's imagine that in humans high blood pressure is due to a dominant gene P and that normal blood pressure is associated with recessive allele p (homozygous recessive creates normal pressure). A man suffers from high blood pressure, as did his father. He has a sister and a brother with normal blood pressure, and his mother also has normal blood pressure. He plans to marry a woman who is heterozygous with regard to these genes. If they have four children, estimate how many of their children will ahve high blood pressure.

What is the man's / Woman's genotype and why?

Explanation / Answer

1) Both partners are heterozygous for the PTC-tasting gene, so their children ought to be split like so: 6 can taste PTC, 2 can't, because six of the eight will be homozygous dominant or heterozygous, both of which exhibit the phenotype. C c C CC cC c cC cc 2) This result is the same as the previous problem. Six kids exhibit the trait and two don't because the parents are both heterozygous. We know the prospective father is heterozygous because his mother did not exhibit the trait (was homozygous recessive) and his father did exhibit it (either heterozygous or homozygous dominant). Had the man's father been homozygous dominant, all of his kids would have high blood pressure because he would have passed on the dominant gene to all of them, but two of them don't, so he must have been heterozygous.