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c. Let us assume that the reaction did not proceed to completion. When you began

ID: 1033523 • Letter: C

Question

c. Let us assume that the reaction did not proceed to completion. When you began the liquid-liquid extraction, the reaction mixture was a solution containing: benzyl alanine methyl ester (~95 mol %), methyl pyruvate (~5 mol %), benzylamine (-5 mol %), NaB(OH)(OAc)3 (~5 mol %, unreacted NaBH(OAC)3 from the reaction, that reacted with water). From the beginning of the liquid-liquid extraction until the isolation of a solid by vacuum filtration, indicate the fate of each of these compounds. For example, you may write: compound X was removed in the organic layer during liquid-liquid extraction (no further explanations are required).

Explanation / Answer

Compound NaB(OH)3 unreacted will be removed in aqueous phase while all others will be removed in organic layer.

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