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1. You are a biochemist who has isolated a new amino acid found in skin secretio

ID: 1032569 • Letter: 1

Question

1. You are a biochemist who has isolated a new amino acid found in skin secretions from a recently discovered amphibian residing in the jungles of Colombia. You give the amino acid a designation of Frg and note that it is toxic with the structure below. Based on your knowledge of biochemistry, how many iohizable protons does Frg possess and where are they on the structure? Estimate each pKa and the pl of this structurally intriguing amino acid? What is its molecular weight? Why would it be toxic? a. b. c. d. NH3 -OH ??- NH3 ??

Explanation / Answer

a) Total no. of ionizable protons is 7

c) No. of carbon atom is 18

No. of oxygen atom is 11

No. of Hydrogen atom is 16

No. of sulphur atom is 2

Molecular weight =( 18×12)+(11×16)+(16×1)+(2×16) =440

d) it is toxic due the presence of two sulphur atoms.