CHEM 432 Biochemistr March 13, 2018 Homework. 10 points: Turn in assigned homewo

Question

CHEM 432 Biochemistr March 13, 2018 Homework. 10 points: Turn in assigned homework from Chapters 17, 15, 12 and 14. Section" Multiple Choice. 60 points: For multiple choice questions, fill in the bubble sheet with a #2 pen S. T your name and associated bubble letters on the answer sheet. For ID, use your student number. Questions 1, which of the following statements apply to the -oxidation of fatty acids? 1. The process takes place in the cytoplasm. E) 2. Carbon atoms are removed from the fatty acid one at a time. 3. Before oxidation, fatty acids are converted to their CoA derivatives. 4. NADP' is the electron acceptor for all oxidations. A) B) 5. The products of -oxidation enter the citric acid cycle for further oxidation. A) 1 and 3 only B) 1, 2, and 3 C) 2 and 5 only D) 4 only E) 3 and 5 only 2. What is the correct order or sequence of intermediates formed during -oxidation? 1. hydroxyl 2. alkene 3. alkane 4. ketone A) 1, 2,3,4 B) 3,4, 1,2 C) 4,3, 1, 2 D) 3, 2, 1,4 E) 4, 2,3, 1 3. Fatty acids are activated to acyl-CoAs and the fatty acyl group is then transferred to carnitine because: A) acyl-CoAs easily cross the mitochondrial membrane, but the fatty acids themselves will not. B) acyl-carnitines readily cross the mitochondrial inner membrane, but acyl-CoAs do not. C) carnitine participates directly in fatty acid -oxidation. D) fatty acids cannot be oxidized unless they are in the activated acyl-carnitine form. E) None of these are true 4. Which of the following are a source of carbon for the synthesis of glucose? A) pyruvate, oxaloacetate and certain amino acids B) all amino acids and nitrogenous bases C) acetoacetate and -hydroxybutyrate D) acetyl-CoA and ketone bodies E) none of these

Explanation / Answer

1.E, process takes place in mitochondria and at a time more than 1 carbon can be release

2.D, first molecule converts to an alkane then acyl carnitene, then hydroxy and at last beta keto

3.B , acyl carnitene readily cross the mitochondrial membrane

4.A

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