18. A common intermediate in the synthesis of ketone bodies and cholesterol is A
ID: 1025489 • Letter: 1
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18. A common intermediate in the synthesis of ketone bodies and cholesterol is A) carnitine B) HMG-COA C) malate D) oxaloacetate E) lipoic acid 19. The principal source of reducing equivalents in fatty acid biosynthesis is A) NADPH B) NADH C) FADH D) NADP E) NAD 20. The sequence of events in the response of hepatocytes (liver cells) to elevated glucagon is: 1. GTP replaces GDP on G-protein 2. adenylyl cyclase is activated 3. glucagon binds to its receptor on the cell surface 4. The G-protein subunit that binds GTP associates with adenylyl cyclase 5, cAMP-dependent protein kinase A is activated A) 2, 4, 1, 3,5 B) 5, 2, 3, 1,4 C) 3, 1, 4, 2,5 D) 3, 2, 1, 4,5 E) 3,5, 4, 2,1 21. De novo purine biosynthesis is distinguished from salvage pathway biosynthesis by: A) use of amino acids as precursors and not nitrogenous bases. B) use of NADH and FADH2 for reducing equivalents C) use of tetrahydrofolate (folic acid) for C: metabolism. D) A and C only are true. E) Aand B only are true. 22. Which of the following is true? A) Muscle cannot use fatty acids as an energy source. B) The brain prefers glucose as an energy source, but can use ketone bodies. C) Equal amounts of energy are stored as glycogen and as triacylglycerol. D) Fatty acids cannot be used as an energy source in humans because humans lack the enzymes neede E) None of these are true. 23. Which of the following statements is false in reference to the synthesis of urea? A) Urea is synthesized as a means to remove ammonia from the body. B) Urea is cleaved from the amino acid arginine by the use of water. C) The cycle is an energy-yielding, ATP producing, series of reactions. D) Amine groups from amino acids are the source of ammonia used in urea synthesis. B) Two amino acid intermediates in the pathway do not occur in proteins. CHEM 432 Exam 3Explanation / Answer
Q no 18 :- HMG-CoA is an important biosynthetic intermediate in the synthesis of ketones and cholesterol . It is formed from acetyl CoA and acetoacetyl CoA by HMG-CoA synthase.
Hence option (b) is correct.
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