1. A denaturing agent is a substance that disrupts the three dimensional structu
ID: 1001541 • Letter: 1
Question
1. A denaturing agent is a substance that disrupts the three dimensional structure of large molecules such as proteins, DNA, or RNA and leads to their denaturation. The conjugate acid of guanidine is most commonly used as a denaturing agent. Shown below are the structures of guanidine and two forms of its conjugate acid A and B. Identify the more stable structures of the conjugate acid_____________. . This structure is more stable than the other because of _______________________
2. Ethyl butanoate shown below is one of the several esters found in mangoes. The most acidic proton in ethyl butanoate would be because the conjugate base obtained by the removal of this proton would be more stable because of___________________
3. Atenolol is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and improve survival after a heart attack. Atenolol is in a class of medications called beta blockers. In the structure of atenolol shown below, the more acidic proton would be ______________
as the conjugate base obtained by the removal of this proton would be more stable because of ______________
Explanation / Answer
1.-
The more stable structures of the conjugate acid___is the B form___
This structure is more stable than the other because of ___protonating the double bonded nitrogen enables effective resonance stabilization. The positive charge can be delocalized across the molecule. Protonating the other nitrogens does not allow for the same degree of resonance stabilization.__
2.-
Ethyl butanoate shown below is one of the several esters found in mangoes. The most acidic proton in ethyl butanoate would be __C__ because the conjugate base obtained by the removal of this proton would be more stable because of_the loss of a proton places a negative charge on a more electronegative atom_
3.-
The more acidic proton would be __B__ as the conjugate base obtained by the removal of this proton would be more stable because of ___the substituent is more electronegative and the pKa of the subtituyent group is lower__
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.