Now I am thinking to change the amount and do it over! here is my new calculatio

Question

Now I am thinking to change the amount and do it over! here is my new calculation So do u think I am in right way with new calculation? If not please give me the detials of right calculation as mine with the table please for 4 chemicals :) thanks I am alwayes rate who help me    2.2.3. Compound Ic A 100-ml two-necked flask equipped with a reflux condenser and a stirrer was charged with carbazole (2.56 g, 15.3 mmol), K2CO3 (10.56 g, 76.52 mmol), p-nitrofluorobenzene (6.5 ml, 61.4 mmol), and DMF (80 ml). The reaction mixture was boiled for 12 h, cooled, and poured into water (500 ml). A yellow precipitate was filtered off, dried, and crystallized from benzene. Yield, 3.79 g (86%); m 208-210 c (lit. m.p. 209-211 °c [9] NMR (400 MHz, CDCl3): 6 7.35 (t, 2H), 7.43-7.751 (m, 4H), 7.77 (d, 2H), 8.14 (d, 2H), 8.46 (d, 2H) ppm Found (%): C, 74.96: H, 43.27; N, 9.85. For C18H12N2O2: Anal. Caled (%): C, 74.99; H, 4.21; N, 9.72.

Explanation / Answer

For the preparation of derrivative of carbazole, the calculations shown above looks alright. However, I would suggest running the reaction for longer periods to see If you get a cleaner product formation. You may choose run times of 24 h and 48 h to compare with 12 h reaction. Generally literature sugests fluronitrobenzene reactions with carbazole to be run for 48 h for complete reaction. Also one may not need such a large excess of base, could be reduced to 2 equivalents instead of 5 equivalent. Along with that, the electrophilic reagent fluronitrobenzene could be used in 1.1 equivalent instead of 4 equivalents. These changes may yield a cleaner product formation and separation would be less cumbersome. Solvent DMF can be about 50 ml.

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